Últimas publicaciones científicas

CONCLUSION: Ultrasound-guided two-point RIB provided postoperative analgesia that was non-inferior to TPVB in patients undergoing three-port thoracoscopic surgery.

CONCLUSION: E-MVD offers comparable efficacy to M-MVD for initial pain relief but potentially offers superior long-term durability (lower recurrence) and a better safety profile. Further validation through randomised trials is necessary to determine if a shift in the surgical standard is warranted. Endoscope-assisted microscopic MVD may be a therapy that represents the best of both surgical techniques, especially in the intermediate term, where more literature is needed to establish the…

Inhibitor of nuclear factor kappa-B kinase subunit epsilon (IKBKE), a member of the serine/threonine kinase family, is an important oncogene in glioblastoma. IKBKE is involved in the progression of multiple tumours in glioblastoma (GBM), including tumour invasion, migration, and proliferation. Here, we report an IKBKE-angiomotin-like protein 2 (Amotl2)-yes-associated protein 1 (YAP1) axis in which IKBKE inhibits the protein expression of Amotl2, while Amotl2 regulates the nuclear transport of…

CONCLUSION: Utilizing the YOLOv11 architecture for automated CTPA analysis yields a highly sensitive and visually interpretable screening mechanism. This artificial intelligence-assisted approach holds substantial promise for reducing missed diagnoses and accelerating patient triage in acute clinical settings.

CONCLUSION: The random forest model integrating multimodal dynamic data accurately predicts SDHC after aSAH with strong external validity; ablation analysis confirmed that incorporating dynamic features significantly improved discrimination (AUC 0.894 vs. 0.831 for the static-only model, ΔAUC = 0.063, p = 0.028), identifying dynamic monitoring data – rather than algorithm choice alone – as a key driver of predictive performance and facilitating early identification and risk stratification of…

CONCLUSION: Spontaneous rupture of a recurrent IDC is exceptional and may be followed by extensive ventricular dissemination and delayed hydrocephalus. This necessitates a profound understanding of the associated risks, enhanced follow-up protocols, and timely intervention.

CONCLUSION: This study successfully developed a logistic regression-based predictive model for pneumonia risk in patients with hemorrhagic stroke. The model demonstrated favorable discrimination and stability. It provides an objective, quantitative basis for early identification of high-risk patients, stratified management, and precise prevention and control, supporting a shift from reactive to proactive complication management.

CONCLUSION: Surgery within 6 h effectively reduces the risk of preoperative rerupture in PaSAH patients and significantly improves long-term outcomes.

CONCLUSION: Microsurgery via a micro-tubular retractor under CT guidance is a feasible and effective approach for the surgical treatment of spinal dural arteriovenous fistulas (SDAVFs). This method achieves precise localization and minimizes surgical trauma by reducing damage to muscles, ligaments, and bony structures, thereby shortening postoperative recovery time. However, long-term follow-up and additional cases are needed to further validate the clinical efficacy of this technique.

Noble gases were chemically inert elements that have attracted increasing interest because of their potential neuroprotective properties. Among them, xenon had long been used as an inhalational anesthetic, while xenon, argon, and helium had also been investigated for possible neuroprotective effects. This narrative review focused on acquired brain injury, particularly ischemic stroke, post-cardiac arrest hypoxic-ischemic brain injury, and traumatic brain injury. Preclinical studies had suggested…

Supplementary motor area (SMA) syndrome is a postoperative complication following SMA tumor resection, characterized by delayed movement initiation and impaired bimanual coordination. Although spontaneous recovery is common, rehabilitation strategies tailored to recovery stages remain unclear. We report a 38-year-old woman who presented with a right SMA tumor (isocitrate dehydrogenase-mutant oligodendroglioma). Preoperatively, she was independent in activities of daily living (ADLs) with no…

Healthcare-associated meningitis caused by extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae is a well-recognized condition after neurosurgical procedures in adults; however, it remains uncommon in children, particularly when detailed microbiological characterization is available. Here we report a case of ESBL-producing K. pneumoniae meningitis with hypervirulent features following neurosurgical intervention in an infant. A previously healthy male infant developed fever and…

CONCLUSION: Parents perceived that participation in medical weight management programs positively impacted household health behaviors. Participants across family systems identified both conscious and unconscious behavioral changes. These findings suggest that parent participation in weight loss programs may have broader implications beyond individual health benefits, and household health dynamics should be considered when managing pediatric obesity.

CONCLUSION: Patients with craniopharyngioma or CNS germ cell tumor had lower levels of social participation and physical activity than healthy participants, and greater apathy was linked to reduced productivity. These findings suggest that joint activity planning and encouragement from caregivers may promote social participation in patients with apathy.

CONCLUSION: This favorable outcome suggests that endoscopic evacuation of ASDH could be proposed as an alternative option for selected young patients with clinical and radiological stability.