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6th Neurosurgery Update

17 March, 2017 administrator Leave a comment

6th Neurosurgery Update

March 17, 2017 — March 18, 2017

Munich, Germany

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Core Journals

Operative Neurosurgery

artesunic_acid - created
Ackermann et al. report on the chemical hybridization approach exemplified by artesunic acid (ARTA) and naturally occurring triterpene betulinic acid (BETA). Artemisinin derived semisynthetic compound artesunic acid (ARTA) and naturally occurring triterpene BETA were used to synthetically couple to the hybrid compound termed 212A. We investigated the impact of 212A and its parent compounds on […]
axl_receptor_tyrosine_kinase
AXL receptor tyrosine kinase Its exceptional role in GBM was presented in previous studies showing that experimental inhibition of the RTK-AXL pathway with dominant negative-mutant glioma cells of AXL receptor (SF126 AXL-DN) suppresses glioma growth and prolongs survival in orthotopic tumor model in mice
gas6
Dysregulation of Axl and its ligand growth arrest-specific 6 (GAS6) is implicated in the pathogenesis of several human cancers. The AXL receptor tyrosine kinase transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6 (
mertk
Mer (MerTK) and Axl receptor tyrosine kinases (RTK) are expressed at abnormally high levels in a variety of malignancies, and these receptors are known to activate strong antiapoptotic signaling pathways that promote oncogenesis. In this study, we found that Mer and Axl mRNA transcript and protein expression were elevated in astrocytic patient samples and cell […]
sunitinib
Sunitinib Martinho et al. provide evidence that AXL activity can modulate sunitinib response in glioblastoma cell lines. We found that AXL knockdown conferred lower sensitivity to sunitinib by rescuing migratory defects and inhibiting apoptosis in cells expressing high AXL basal levels. Accordingly, overactivation of AXL by its ligand GAS6 rendered AXL positive glioblastoma cells more […]

Wiki

glioblastoma_recurrente
Glioblastoma recurrente El glioblastoma recurre en la gran mayoría de los pacientes dentro de los 2-3 años. Diagnóstico diferencial La evaluación multiparamétrica RM de 3-T basada en espectroscopía RM (1H-MRSI), imágenes por difusión (DWI) e imagen de perfusión ponderada (PWI), además de la RM convencional es una herramienta útil para discriminar la recurrencia del tumor […]
cuidado_de_herida_quirurgica
Vigilancia de temperatura y aspecto desde el 2º al 4º día del postoperatorio (diagnostico precoz de seromas e infecciones). analgesia optima en los primeros 5-6 dias, a partir de aquí el dolor es signo de complicación: - localizacion. - umbral.
i4534
I4534 Mujer de 60 años de edad que ingresa por dehiscencia de la herida-infección de herida quirúrgica y fístula de líquido cefalorraquídeo. Alergia al medio de contraste yodado Intervenida por Glioma de alto grado en giro supramarginal izquerdo. Tratamiento con radioterapia y quimioterapia según protocolo. Recidiva en control de imagen que precisa reintervención quirúrgica. Enfermedad […]
herida_quirurgica
Herida quirúrgica TODA AQUELLA SOLUCION DE CONTINUIDAD DE PIEL Y/O MUCOSAS Y TEJIDOS SUBYACENTES PROVOCADA POR EL CIRUJANO CON EL FIN DE ACCEDER A CUALQUIER TERRITORIO DEL ORGANISMO Cuidados ver cuidado de herida quirúrgica.
ceftazidima - creado
Bactericida. Inhibe la síntesis de pared bacteriana. Altamente estable a la mayoría de ß-lactamasas clínicamente importantes. Indicaciones terapéuticas Ceftazidima Tto. de las infecciones que se enumeran a continuación en ads. y niños incluyendo recién nacidos (desde el nacimiento): neumonía nosocomial, infecciones broncopulmonares en fibrosis quística, meningitis bacteriana, otitis media supurativa crónica y externa maligna; infecciones […]

AANS Neurosurgeon

Metabolic Enzyme Fuels Molecular Machinery of Memory 22 June, 2017
Penn study finds epigenetics key to laying down spatial memories in mouse brain, providing possible new neurological medications Understanding how memories are made, retrieved and eventually fade over a lifetime is the stuff of poems and song. To medical researchers, solving the mysteries of memory is even more elusive. Researchers surmise that “laying down” a […]
Chronic Pain May Be Due to Receptors That Hide Within Nerve Cells 22 June, 2017
Study, in rodents, may lead to development of a new class of medications for chronic pain that is longer-lasting, with fewer side effects A study led by Columbia University Medical Center (CUMC) has shown that chronic pain may occur when pain receptors migrate from the nerve cell’s surface to the cell’s inner chambers, out of […]
Scientists ID 100 Memory Genes, Open New Avenues of Brain Study 21 June, 2017
Scientists have identified more than 100 genes linked to memory, opening new avenues of research to better understand memory processing in the human brain. A study at the Peter O’Donnell Jr. Brain Institute includes the results of a new strategy to identify genes that underlie specific brain processes. This strategy may eventually help scientists develop […]
In MS, Problems Reading Social Cues May Be Tied to Brain Changes 21 June, 2017
For people with multiple sclerosis (MS), an impaired ability to understand how others feel and think may be linked to subtle brain changes. “Understanding how MS affects the ‘social brain’ has not been well studied, but the ability to interpret other people’s feelings and intentions may influence people’s ability to maintain a job and their […]
Infection With Seasonal Flu May Increase Risk of Developing Parkinson’s Disease 20 June, 2017
Most cases of Parkinson’s have no known cause, and researchers continue to debate and study possible factors that may contribute to the disease. Research suggests that a certain strain of influenza virus predisposes mice to developing pathologies that mimic those seen in Parkinson’s disease. “This study has provided more evidence to support the idea that environmental […]
Gray Matter Density Increases During Adolescence 20 June, 2017
Study reveals new methods of characterizing differences between youth and adult, male and female brains For years, the common narrative in human developmental neuroimaging has been that gray matter in the brain – the tissue found in regions of the brain responsible for muscle control, sensory perception such as seeing and hearing, memory, emotions, speech, […]
Study Provides Better Understanding of How Brain Tumors ‘Feed’ 19 June, 2017
New findings explain how the enzyme ACSS2 aids tumors in a nutrient-starved environment offering potential new treatment approaches All cancer tumors have one thing in common – they must feed themselves to grow and spread, a difficult feat since they are usually in a tumor microenvironment with limited nutrients and oxygen. A study at The […]
Cellular Stress in the Brain May Contribute to Non-Alcoholic Fatty Liver Disease 19 June, 2017
George Washington University researchers find a connection between cellular stress in the brain and non-alcoholic fatty liver disease Disruptions in a protein folding process occurring in the brain, known as endoplasmic reticulum (ER) stress, may cause non-alcoholic fatty liver disease, independent of other factors. A research team at the George Washington University (GW) published their […]
Stroke Risk Factors for Pregnant Women With Preeclampsia Uncovered 16 June, 2017
Infections, hypertension, bleeding disorders and clot-forming conditions increase stroke risk during and after childbirth Women with preeclampsia, a common complication of pregnancy, face a heightened risk of stroke during pregnancy and postpartum if they have urinary tract infections, chronic high blood pressure or clotting or bleeding disorders, according to a study by Columbia University Medical […]
Cannabidiol Reduces Seizures in Children with Severe Epilepsy 16 June, 2017
Randomized placebo-controlled clinical trial shows decline in seizures with cannabidiol in children with drug-resistant Dravet syndrome Results from a double-blind, placebo-controlled trial revealed that children with Dravet syndrome, a severe form of epilepsy, had fewer seizures after taking a daily oral solution of the cannabis compound called cannabidiol, which does not have the psychoactive properties of […]

Journals

LATEST POSTS-PUBMED

neurosurgery; +122 new citations 22 June, 2017

Neurosurgery

Most popular

Acta Neurochirurgica

Bi-nostril transseptal endoscopic approach to the sphenoidal gate. A new technique
Carotid plaque with expansive arterial remodeling is a risk factor for ischemic complication following carotid artery stenting
Erratum to: Is capsulectomy a feasible and useful measure in internal pulse generator replacement procedures? A technical note on the use of the PEAK PlasmaBlade™
De novo vertebral artery dissecting aneurysm after internal trapping of the contralateral vertebral artery
Erratum to: Correlation of electrode position and clinical outcomes in Globus pallidus stimulation for dystonia
Endoscopic approach via the interhemispheric fissure: the role of an endoscope in a surgical case of multiple falcine lesions
Clipping of ruptured intracranial aneurysms in a hybrid room environment—a case-control study
Cerebral aneurysm neck diameter is an independent predictor of progressive occlusion after stent-assisted coiling
Stereotactic MR-guided focused ultrasound deep brain lesioning: the resurrection of posteroventral pallidotomy and thalamotomy for Parkinson’s disease?
Reply to “Post-surgical mutism and catatonia”

Stroke

Letter by Nighoghossian Regarding Article, “Risk of Pulmonary Embolism After Cerebral Venous Thrombosis” [Letter to the Editor]
Letter by Ng et al Regarding Article, “Cervical Carotid Pseudo-Occlusions and False Dissections: Intracranial Occlusions Masquerading as Extracranial Occlusions” [Letter to the Editor]
Letter by McGowan Regarding Article, “Quality of Acute Care and Long-Term Quality of Life and Survival: The Australian Stroke Clinical Registry” [Letter to the Editor]
Response by Grossberg et al to Letter Regarding Article, “Cervical Carotid Pseudo-Occlusions and False Dissections: Intracranial Occlusions Masquerading as Extracranial Occlusions” [Letter to the Editor]
Letter by Machado-Alba et al Regarding Article, “Rivaroxaban Versus Dabigatran or Warfarin in Real-World Studies of Stroke Prevention in Atrial Fibrillation: Systematic Review and Meta-Analysis” [Letter to the Editor]
Letter by Sposato et al Regarding Article, “Stroke as the Initial Manifestation of Atrial Fibrillation: The Framingham Heart Study” [Letter to the Editor]
Correction to: Predictors of the Aspiration Component Success of a Direct Aspiration First Pass Technique (ADAPT) for the Endovascular Treatment of Stroke Reperfusion Strategy in Anterior Circulation Acute Stroke [Correction]
Response by Lubitz et al to Letter Regarding Article, “Stroke as the Initial Manifestation of Atrial Fibrillation: The Framingham Heart Study” [Letter to the Editor]
Response by Merkler et al to Letter Regarding Article, “Risk of Pulmonary Embolism After Cerebral Venous Thrombosis” [Letter to the Editor]
Letter by Murray and Barrow Regarding Article, “Trends in Recruitment Rates for Acute Stroke Trials, 1990-2014” [Letter to the Editor]

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Latest News

Mannitol for intraoperative brain relaxation 23 June, 2017
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BNOS 2017 – Conference of the British Neuro-oncology Society 21 June, 2017
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VI Ukrainian Congress of Neurosurgery 14 June, 2017
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Joint Annual Meeting 2017 of the Swiss Society of Neurosurgery (SSNS), the Swiss Society of Neuroradiology (SSNR), IG-NOPPS 8 June, 2017
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Noticias de la Sociedad Española

BECA XVIII CURSO TEÓRICO-PRÁCTICO DE MICROCIRUGÍA 21 June, 2017
XV PREMIO NACIONAL DE INVESTIGACIÓN COLEGIO DE MÉDICOS DE CÓRDOBA, PATROCINADO POR CAIXABANK 21 June, 2017
ACREDITACIÓN DE LABORATORIOS COMO CENTRO PARA FORMACIÓN EN NEUROANATOMÍA 13 June, 2017
NUEVA OFERTA DE TRABAJO JUNIO 13 June, 2017
EANS NEWS 1 June, 2017
BECAS PREDOCTORALES EN NEUROCIENCIA – 2017 DE LA FUNDACIÓN TATIANA PÉREZ DE GUZMÁN EL BUENO 1 June, 2017
RENOVACIÓN VOCAL DE JUVENTUD 26 May, 2017
BECAS BAXTER SENEC-GT PATOLOGÍA VASCULAR 25 May, 2017
BECA SENEC 2017 25 May, 2017
MEMORIA BAXTER SENEC-GT VASCULAR 10 May, 2017

World Neurosurgery

Clinical efficacy and its prognostic factor of percutaneous endoscopic lumbar annuloplasty and nucleoplasty for treatment of patients with discogenic low back pain
Risk of Aneurysm Residual Regrowth, Recurrence, and De Novo Aneurysm Formation after Microsurgical Clip Occlusion Based on Follow-up with Catheter Angiography
Intraventricular Cavernomas of the Third Ventricle: Report of Two Cases and a Systematic Review of the Literature
Management of Residual Tumor after Limited Subtotal Resection of Large Vestibular Schwannomas: Lessons Learned and a Rationale for Specialized Care
Novel Oral Anticoagulants in Patients Undergoing Cranial Surgery
Microsurgical Bypass Training Rat Model: Part 1 –Technical Nuances of Exposure of the Aorta and Iliac arteries
Distribution and network of basal temporal language areas: a study of the combination of electric cortical stimulation and diffusion tensor imaging
The clinical features and surgical outcomes of spinal cord tanycytic ependymomas: a report of 40 cases
Is It Feasible to Treat Odontoid Fractures via Primary Posterior Reduction and Fixation without Fusion?
Kinase activity in recurring primary Skull Base Chordomas and Chondrosarcomas: identification of novel pathways of oncogenesis and potential drug targets

Neurosurgery Blog

Faces of Neurosurgery: Dr. Behnam Badie 20 June, 2017
Voices of Our Patients — Becoming Legendary Requires Being Bold 9 June, 2017
AANS Annual Meeting Spotlight: Idea Economy — It’s Not Brain Surgery 5 June, 2017
ACA: Cost, Coverage, Choice and Change 30 May, 2017
A History of #HealthReform 25 May, 2017
60 is the New 40: Did You Ask Your Spine About That? 20 May, 2017
CNS Spotlight: Congress Quarterly Presents the CNS 2016 Annual Report 18 May, 2017
AANS Neurosurgeon Spotlight: March 2017 – Concurrent Surgery 24 April, 2017
Medicare Expenditures Variation after Implementation of the Affordable Care Act 13 April, 2017
Open Payments: What Neurosurgeons Need to Know and How Accurate is the Data? 7 April, 2017

Journal of Neurotrauma

Focal Electroencephalographic Changes Index Post-Traumatic Confusion and Outcome
Recovery from Coma Post-Cardiac Arrest Is Dependent on the Orexin Pathway
The Relationship between Trans-Lesional Conduction, Motor Neuron Pool Excitability, and Motor Function in Dogs with Incomplete Recovery from Severe Spinal Cord Injury
Targeting Translational Successes through CANSORT-SCI: Using Pet Dogs To Identify Effective Treatments for Spinal Cord Injury
The Alternative Receptor for Complement Component 5a, C5aR2, Conveys Neuroprotection in Traumatic Spinal Cord Injury
Improved Diagnosis of Cervical Spondylotic Myelopathy with Contact Heat Evoked Potentials
Atraumatic Spine Distraction Induces Metabolic Distress in Spinal Motor Neurons
Functional Outcome Prediction after Traumatic Spinal Cord Injury Based on Acute Clinical Factors
Dynamic “Range of Motion” Hindlimb Stretching Disrupts Locomotor Function in Rats with Moderate Subacute Spinal Cord Injuries
Spinal Cord Injury Leads to Hyperoxidation and Nitrosylation of Skeletal Muscle Ryanodine Receptor-1 Associated with Upregulation of Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4

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