Neurosurgery December 2016

jackson_pratt_drainage - created
Jackson Pratt drainage Jackson-Pratt drains (JPDs) are commonly employed in pediatric craniofacial reconstructive surgery (CRFS) to reduce postoperative wound complications, but their risk profile remains unknown. Perioperative blood loss and volume shifts are major risks of CFRS. The goal of this study was to evaluate the risks of JPD usage in CFRS, particularly with regard […]
cylindromatosis
Cylindromatosis Cylindromatosis (CYLD) is a tumor suppressor that regulates signaling pathways by acting as a deubiquitinase. CYLDdown-regulation occurred in several malignancies, with tumor-promoting effects. Although Guo et al. found loss of CYLD expression in hypoxic regions of human glioblastoma multiforme (GBM), biological roles of CYLD in GBM remain unknown.
mir_130b - created
miR-130b expression was upregulated in glioma tissues and cell lines. Kaplan-Meier analysis indicated that the upregulation of miR-130b expression correlated with poor prognoses in glioma patients. Multivariate analysis demonstrated that this upregulation and a high-grade classification were independent factors that both predicted poor outcomes for glioma patients. Dual-luciferase assays identified that the
microrna
MicroRNA MicroRNAs (miRNAs) are small noncoding RNAs of 20-25 nucleotides in length. They are considered as the cellular regulators which posttranscriptionally modulate gene expression in diverse biological processes including cell development and immunity. Remarkably, 98% of the RNA within a cell is not translated into
mir_181d
Su XW, Lu G, Leung CK, Liu Q, Li Y, Tsang KS, Zhao SD, Chan DTM, Kung HF, Poon WS. miR-181d regulates human dendritic cell maturation through NF-κB pathway. Cell Prolif. 2017 Jul 21. doi: 10.1111/cpr.12358. [Epub ahead of print] PubMed PMID: 28731516.

traumatismo_craneoencefalico_leve - [Clínica]
Traumatismo craneoencefálico leve Definición El término conmoción cerebral se utiliza a menudo como un sinónimo de TCE leve, pero probablemente describe un subconjunto de daño cerebral más leve y se define como una alteración traumática del estado mental que puede o no implicar la pérdida de la conciencia.
epilepsia_postraumatica - [Epidemiología]
Epilepsia postraumática Crisis epiléptica relacionada con el traumatismo craneoencefálico (TCE) de cualquier naturaleza. Tipos Crisis postraumáticas inmediatas a immediatamente despues o a los pocos minutos de las crisis, suelen ser crisis generalizadas y no tienen valor pronóstico en cuanto a la presentación de una epilepsia posterior.
traumatismo_craneoencefalico - [Complicaciones]
Traumatismo craneoencefálico Alteración en la función cerebral, u otra evidencia de patología cerebral, causada por una fuerza externa (Menon y col., 2010). Epidemiología La epidemiología de la lesión cerebral traumática se estudia a menudo utilizando la Clasificación (CIE-9-MC). Los estudios recientes sugieren que estos códigos pueden subestimar la carga de la lesión cerebral traumática debido […]
convulsion
Convulsión La convulsión es, un síntoma transitorio caracterizado por actividad neuronal en el cerebro que conlleva a hallazgos físicos peculiares como la contracción y distensión repetida y temblorosa de uno o varios músculos de forma brusca y generalmente violenta, así como de alteraciones del estado mental del sujeto y trastornos psíquicos tales como déjà vu […]
signo_de_los_ojos_de_mapache - creado
“Signo de los Ojos de Mapache“, el cual tiene su origen por una fractura a nivel del piso anterior de la base del cráneo y está representado por una equimosis periorbitaria usualmente en ambos ojos.

Researchers Define Structure of Key Enzyme Implicated in Cancer, Neurological Disease 21 July, 2017
A Stony Brook University-led team of researchers has determined the structure of a key enzyme involved with cell growth regulation in cancer and neurodegenerative diseases, including Alzheimer’s disease. The finding reveals the first visualization of the enzyme and could provide insight into how the enzyme is activated. The enzyme, neutral sphingomyelinase (nSMase2), is one of the […]
Risk of Developing Alzheimer’s Disease Linked to a Network of Genes Associated With Myeloid Cells 21 July, 2017
Many genes linked to late-onset Alzheimer’s disease (AD) are expressed in myeloid cells and regulated by a single protein, according to research conducted at the Icahn School of Medicine at Mount Sinai. Mount Sinai researchers led an international, genome-wide study of more than 40,000 people with and without the disease and found that innate immune […]
Study: Exposure to Light Causes Emotional and Physical Responses in Migraine Sufferers 20 July, 2017
Researchers identify novel connections between neurons in the eye and neurons in the brain People experiencing migraines often avoid light and find relief in darkness. A new study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has revealed a previously unknown connection between the light-sensitive nerve cells in the eye and centers in […]
Leisure Activities Lower Blood Pressure in Alzheimer’s Caregivers 20 July, 2017
Going for a walk outside, reading, listening to music — these and other enjoyable activities can reduce blood pressure for elderly caregivers of spouses with Alzheimer’s disease, suggests a study. “Greater engagement in pleasant leisure activities was associated with lowered caregivers’ blood pressure over time,” according to the report by Brent T. Mausbach, PhD, of […]
New Biomarker Assay Detects Neuroblastoma With Greater Sensitivity 19 July, 2017
Improved disease assessment aids in prediction of relapse in children Investigators at The Saban Research Institute of Children’s Hospital Los Angeles have developed and tested a new biomarker assay for quantifying disease and detecting the presence of neuroblastoma even when standard evaluations yield negative results for the disease. In a study, led by Araz Marachelian, […]
dfhgdfg 19 July, 2017
dfghdfgh The post dfhgdfg appeared first on AANS Neurosurgeon.
Extra-virgin Olive Oil Preserves Memory and Protects Brain Against Alzheimer’s Disease, New Research at Temple Shows 19 July, 2017
The Mediterranean diet, rich in plant-based foods, is associated with a variety of health benefits, including a lower incidence of dementia. Now, researchers at the Lewis Katz School of Medicine at Temple University (LKSOM) have identified a specific ingredient that protects against cognitive decline: extra-virgin olive oil, a major component of the Mediterranean diet. In […]
Parkinson’s is Partly an Autoimmune Disease, Study Finds 18 July, 2017
First direct evidence that abnormal protein in Parkinson’s disease triggers immune response Researchers have found the first direct evidence that autoimmunity — in which the immune system attacks the body’s own tissues — plays a role in Parkinson’s disease, the neurodegenerative movement disorder. The findings raise the possibility that the death of neurons in Parkinson’s […]
What Percentage of ALS is Genetic? 18 July, 2017
Up to 90 percent of people with amyotrophic lateral sclerosis (ALS) report that they have no family history of the disease. Now, new research has found approximately 17 percent of such ALS cases may be caused by a gene mutation, according to a study. Often referred to as Lou Gehrig’s disease, ALS is a progressive […]
Identified Brain Circuitry Bridges Neural and Behavioral Roles in Post-traumatic Stress Disorder 17 July, 2017
Specific cerebral circuitry bridges chemical changes deep in the brain and the more outward behavioral expressions associated with post-traumatic stress disorder (PTSD), which could lead to more objective biomarkers for the disorder, according to a comprehensive review of rapidly changing data. In this latest, comprehensive review, the authors — from the Steven and Alexandra Cohen Veterans Center (CVC) in […]

Neurocirugia.com

Neurosurgery December 2016

Intraoperative Near-Infrared Optical Imaging Can Localize Gadolinium-Enhancing Gliomas During Surgery

Statements of Agreement From the Targeted Evaluation and Active Management (TEAM) Approaches to Treating Concussion Meeting Held in Pittsburgh, October 15-16, 2015

Focused Ultrasound Enhances Central Nervous System Delivery of Bevacizumab for Malignant Glioma Treatment

Gross Total Resection of Glioblastoma Improves Overall Survival and Progression-Free Survival Compared to Subtotal Resection or Biopsy Alone

Long-term Training With a Brain-Machine Interface-Based Gait Protocol Induces Partial Neurological Recovery in Paraplegic Patients

IL-21 Receptor Modulates Ischemic Severity in Stroke

Human Cerebral Cortex Map 2.0

A Randomized Clinical Trial of Aggressive Blood Pressure Control in Patients With Acute Cerebral Hemorrhage

“Tag Team” Glioblastoma Therapy: Results From a Phase 1 Trial of Toca 511 and 5-Fluorocytosine for Recurrent High-Grade Glioma

Abnormal Cerebrospinal Fluid Flow: A New Model of Idiopathic Scoliosis

Neuroregeneration: North America’s First Human Stem Cell Trial for Stroke

Directionality of Medial Prefrontal Cortex and Hippocampal Interactions Is Task-Dependent

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