University of Rochester Medical Center Receives Grants to Explore Role of Brain’s “Garbage Truck” in Mini-Strokes and Trauma

Over $4.5 million in new grants has been given to the lab of University of Rochester Medical Center scientist Maiken Nedergaard, M.D., D.M.Sc.  Her research explores the important role the brain’s waste disposal system may play in a range of neurological disorders. The new awards will further the understanding of how small vessel disease and traumatic brain injury can give rise to cognitive and behavioral problems.

Nedergaard and her colleagues first unveiled the brain’s unique method of removing waste – coined the glymphatic system – in a paper in Science Translational Medicine in 2012.  The research revealed that the brain possesses a circulation network that piggybacks on blood vessels and uses cerebral spinal fluid to flush away waste products from brain tissue.  Based on this original finding, the team has gone on to show that the glymphatic system works primarily while we sleep, could be a key player in diseases like Alzheimer’s, and is disrupted after traumatic brain injury.

Read more about her exciting research here.

Leave a Reply