In a matched cohort of trauma patients, pre injury ibuprofen use was not associated with progression of initial intracranial hemorrhage and the need for neurosurgical intervention. Preinjury use of Ibuprofen as an independent variable should not warrant the need for a routine repeat head computed tomography (RHCT) scan 1)
1) Zangbar B, Pandit V, Rhee P, Khalil M, Kulvatunyou N, O’Keeffe T, Tang A, Gries L, Green DJ, Friese RS, Joseph B. Clinical outcomes in patients on preinjury ibuprofen with traumatic brain injury. Am J Surg. 2014 Aug 1. pii: S0002-9610(14)00366-3. doi: 10.1016/j.amjsurg.2014.05.027. [Epub ahead of print] PubMed PMID: 25190545.