First use of fluorescein sodium guided resection

Fluorescein sodium guided resection

The first use of fluorescence for brain tumour surgery was in 1948 by G.E. Moore 1) using fluorescein sodium, a strongly fluorescing and non-toxic agent.

MOORE GE, PEYTON WT, et al. The clinical use of fluorescein in neurosurgery; the localization of brain tumors. J Neurosurg. 1948 Jul;5(4):392-8. PubMed PMID: 18872412.

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